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ASN KIDNEY WEEK 2025

Viele Forschungsarbeiten zu ADTKD

20.10.2025 - Auf der Kidney Week der Amerikanischen Gesellschaft für Nephrologie (ASN) vom 5. bis 9. November werden mehrere Forschungsarbeiten zu ADTKD vorgestellt, vor allem zur Unterform ADTKD-UMOD. Interessant sind etwa Beiträge zum Einfluss einer Diät auf das Fortschreiten der Erkrankung.

Hier finden Sie eine Übersicht.

ADTKD-UMOD

• [FR-OR047] Devuyst O et al. Allele-Selective Antisense Oligonucleotide Targeting Uromodulin Reduces Toxic Aggregates and Rescues Kidney Damage in Models of UMOD-Related Autosomal Dominant Tubulointerstitial Kidney Disease
  7. November 2025,  04:40 PM-04:50 PM
  Ort: Room 360A, Convention Center
• [FR-OR048] Fang Y et al. Mesencephalic Astrocyte-Derived Neurotrophic Factor Orchestrates Endoplasmic Reticulum (ER)-Mitochondrial Calcium Homeostasis in Genetic CKD
  7. November 2025, 04:50 PM-05:00 PM
  Ort: Room 360A, Convention Center
• [SA-PO0620] Zivna M et al. Early Phenotype in Umod-Associated Autosomal Dominant Tubulointerstitial Kidney Disease Knockin Mice
   8. November 2025,  10:00 AM-12:00 PM
  Ort: Exhibit Hall, Convention Center
• [SA-PO0621] Cratere MG et al. Calorie Restriction Promotes Degradation of Mutant Uromodulin and Ameliorates Inflammation and Fibrosis in UMOD-Related Autosomal Dominant Tubulointerstitial Kidney Disease
  8. November, 2025, 10:00 AM-12:00 PM
  Ort: Exhibit Hall, Convention Center
• [SA-PO0623] Mariniello M et al.  Dietary Interventions Enhancing Autophagy Clear Uromodulin Aggregates and Slow Disease Progression in UMOD-Related Autosomal Dominant Tubulointerstitial Kidney Disease
   8. November 2025,  10:00 AM-12:00 PM
  Ort: Exhibit Hall, Convention Center
• [SA-PO0622] Lake J et al. Lipocalin-2 Is Induced by Uromodulin Aggregates but Does Not Affect Kidney Disease Progression in UMOD-Related Autosomal Dominant Tubulointerstitial Kidney Disease
  8. November 2025, 10:00 AM-12:00 PM
  Location: Exhibit Hall, Convention Center
• [SA-PO0624] Gu C et al. Impaired Autophagy in Human Kidney Organoids of Autosomal Dominant Tubulointerstitial Kidney Disease
  8. November 2025, 10:00 AM-12:00 PM
  Ort: Exhibit Hall, Convention Center
• [PUB174] Cardenas E et al.  At Last, the Culprit Is Found: Autosomal Dominant Tubulointerstitial Kidney Disease
  Publication Only
• [PUB179] Sharma Divyadarshini D et al. Beyond Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Cysts: Uncovering Uromodulin Kidney Disease in a Young Adult with Gout and CKD
    Publication Only

ADTKD-MUC1

• [PUB166] Guo W et al. Diagnostic Odyssey of a Case of Autosomal Dominant Tubulointerstitial Kidney Disease MUC-1 (ADTKD MUC-1)
   Publication Only

ADTKD-REN

• [SA-PO0619] REN p.L16del Mutation Is Associated with a Milder In Vitro and Clinical Phenotype Compared with Other Signal Peptide Mutations 
   8. November, 2025   10:00 AM - 12:00 PM
  Ort: Exhibit Hall, Convention Center

Weitere Themen

• [SA-PO0617] Kidd K et al. Outcomes of Referrals to the Wake Forest Autosomal Dominant Tubulointerstitial Kidney Disease Registry
  8. November, 2025 | 10:00 AM-12:00 PM
  Ort: Exhibit Hall, Convention Center
•  [SA-PO0618] Czarnecki PG et al. Truncating Mutations in BICC1 Cause Autosomal Dominant Tubulointerstitial Kidney Disease
  8. November 08, 2025 | 10:00 AM-12:00 PM
  Ort: Exhibit Hall, Convention Center